Ono received from the University of Tokyo his undergraduate degree in 1984, his master's degree in 1987, and his Ph.D. in 1990.[2][3] Within symplectic geometry, his research has focused on Floer theory and holomorphic symplectic geometry involving holomorphic curves and pseudoholomorphic curves and their applications. He has collaborated extensively with Kenji Fukaya, Yong-Geun Oh, and Hiroshi Ohta (see Fukaya category).
In a joint work with K. Fukaya, he constructed Floer cohomology of Hamiltonian diffeomorphisms on arbitrary closed symplectic manifolds as well as Gromov-Witten invariants. Using Novikov-Floer cohomology, he proved the -flux conjecture. In recent years, he has been collaborating with Fukaya, Oh and Ohta in Floer theory for Lagrangian submanifolds and its implications in symplectic geometry and homological mirror symmetry.[1]