Safran was an executive producer and writer on The CW television series Gossip Girl and was the executive producer and showrunner for the second season of the NBC television series Smash.[3] He shared writing credits with director Shana Feste for the screenplay of the 2014 remake of the 1981 film Endless Love.[4]
Safran was the creator, executive producer and showrunner (seasons one and two) of the ABC thriller drama series Quantico.[5][6] Recently, he was credited as the creator, executive producer and showrunner for the Netflix musical television series Soundtrack.[7][8]
He is set to create, executive produce and showrun the 2021 sequel series Gossip Girl for HBO Max.[9] Safran is developing an untitled ghost drama for AMC with Annapurna Television.[10]