In this Catalan name, the first or paternal surname is Cardona and the second or maternal family name is de Gandia; both are generally joined by the conjunction "i".
He was Canon and Archedian in Barcelona, perpetual administrator of the abbey of Santa Maria de Solsona and ecclesiastical deputy of the Deputation of the General of Catalonia. In 1445 he was appointed Bishop of Vich. He endorsed the election of Pope Nicholas V. In 1459 he was transferred to the Diocese of Girona and in 1461 to Urgell.
Pope Pius II created him cardinal in the consistory of 18 December 1461. Cardona never went to Rome to receive the cardinal cape and did not participate in the 1464 papal conclave (election of Paul II).