Dumped by her husband who wants to start a new life with another woman, Jeanne, 38 and mother of two children, decides to no longer live with a man. While she wakes up at dawn to go to the toilet, she does her business standing up without realizing it until she goes back to bed and discovers that she has a penis. Between fits of laughter with her friend Marcelle and panic attacks at her gynecologist, Jeanne tries as best she can to live with this new situation. But things get more complicated when her colleague Merlin falls in love with her.