Human rhinovirus internal cis-acting regulatory element

Human rhinovirus internal cis-acting regulatory element (CRE)
Predicted secondary structure and sequence conservation of Rhino_CRE
Identifiers
Symbol	Rhino_CRE
Rfam	RF00220
Other data
RNA type	Cis-reg
Domain(s)	Viruses
SO	SO:0000233
PDB structures	PDBe

Human rhinovirus internal cis-acting regulatory element (CRE) is a CRE from the human rhinoviruses. The CRE is located within the genome segment encoding the capsid proteins so is found in a protein coding region. The element is essential for efficient viral replication and it has been suggested that the CRE is required for initiation of minus-strand RNA synthesis.[1]

See also

• Human parechovirus 1 (HPeV1) cis regulatory element (CRE)
• Rotavirus cis-acting replication element (CRE)

References

1. McKnight KL, Lemon SM (December 1998). "The rhinovirus type 14 genome contains an internally located RNA structure that is required for viral replication". RNA. 4 (12): 1569–1584. doi:10.1017/S1355838298981006. PMC 1369726. PMID 9848654.

External links

• Page for Human rhinovirus internal cis-acting regulatory element (CRE) at Rfam