Glutaminyl-trna synthase (glutamine-hydrolyzing)-like 1

QRSL1
Identifiers
Aliases	QRSL1, GatA, glutaminyl-tRNA synthase (glutamine-hydrolyzing)-like 1, glutaminyl-tRNA amidotransferase subunit A, glutaminyl-tRNA amidotransferase subunit COXPD40
External IDs	OMIM: 617209; MGI: 1923813; HomoloGene: 6699; GeneCards: QRSL1; OMA:QRSL1 - orthologs
Gene location (Human) Chr. Chromosome 6 (human)[1] Band 6q21 Start 106,629,578 bp[1] End 106,668,417 bp[1]
Gene location (Mouse) Chr. Chromosome 10 (mouse)[2] Band 10|10 B2 Start 43,750,184 bp[2] End 43,777,741 bp[2]
RNA expression pattern Bgee Human Mouse (ortholog) Top expressed in muscle of arm biceps brachii triceps brachii muscle Skeletal muscle tissue of biceps brachii thoracic diaphragm vastus lateralis muscle glutes gastrocnemius muscle gonad right ventricle Top expressed in substantia nigra Paneth cell retinal pigment epithelium facial motor nucleus digastric muscle ciliary body motor neuron condyle sternocleidomastoid muscle fossa More reference expression data BioGPS n/a
Gene ontology Molecular function nucleotide binding ligase activity ATP binding glutaminyl-tRNA synthase (glutamine-hydrolyzing) activity amidase activity protein binding carbon-nitrogen ligase activity, with glutamine as amido-N-donor Cellular component glutamyl-tRNA(Gln) amidotransferase complex mitochondrion Biological process regulation of protein stability protein biosynthesis mitochondrial translation glutaminyl-tRNAGln biosynthesis via transamidation Sources:Amigo / QuickGO
Orthologs Species Human Mouse Entrez 55278 76563 Ensembl ENSG00000130348 ENSMUSG00000019863 UniProt Q9H0R6 Q9CZN8 RefSeq (mRNA) NM_018292 NM_001081054 RefSeq (protein) NP_060762 NP_001074523 Location (UCSC) Chr 6: 106.63 – 106.67 Mb Chr 10: 43.75 – 43.78 Mb PubMed search [3] [4]
Wikidata
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Glutaminyl-tRNA synthase (glutamine-hydrolyzing)-like 1 is a protein that in humans is encoded by the QRSL1 gene. [5]

References

1. GRCh38: Ensembl release 89: ENSG00000130348 – Ensembl, May 2017
2. GRCm38: Ensembl release 89: ENSMUSG00000019863 – Ensembl, May 2017
3. "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
4. "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
5. "Entrez Gene: Glutaminyl-tRNA synthase (glutamine-hydrolyzing)-like 1". Retrieved 2018-05-17.

Further reading

• Vieira AR, McHenry TG, Daack-Hirsch S, Murray JC, Marazita ML (September 2008). "Candidate gene/loci studies in cleft lip/palate and dental anomalies finds novel susceptibility genes for clefts". Genet. Med. 10 (9): 668–74. doi:10.1097/GIM.0b013e3181833793. PMC 2734954. PMID 18978678.
• Nagao A, Suzuki T, Katoh T, Sakaguchi Y, Suzuki T (September 2009). "Biogenesis of glutaminyl-mt tRNAGln in human mitochondria". Proc. Natl. Acad. Sci. U.S.A. 106 (38): 16209–14. Bibcode:2009PNAS..10616209N. doi:10.1073/pnas.0907602106. PMC 2752530. PMID 19805282.