Fowler had its start in the 1850s when the railroad was extended to that point.[2] A post office called Fowler's Station was established in 1857, and the name was changed to Fowler in 1869.[3]
As of the 2020 census[5] there were 154 people, 44 households, and 18 families residing in the CDP. The population density was 1,140.74 inhabitants per square mile (440.44/km2). There were 70 housing units at an average density of 518.52 per square mile (200.20/km2). The racial makeup of the CDP was 87.01% White, 0.65% Native American, 1.95% Asian, 1.30% from other races, and 9.09% from two or more races. Hispanic or Latino of any race were 5.84% of the population.