Formyl-CoA hydrolase

formyl-CoA hydrolase
Identifiers
EC no.	3.1.2.10
CAS no.	9025-91-6
Databases
IntEnz	IntEnz view
BRENDA	BRENDA entry
ExPASy	NiceZyme view
KEGG	KEGG entry
MetaCyc	metabolic pathway
PRIAM	profile
PDB structures	RCSB PDB PDBe PDBsum
Gene Ontology	AmiGO / QuickGO
Search PMC articles PubMed articles NCBI proteins

The enzyme formyl-CoA hydrolase (EC 3.1.2.10) catalyzes the reaction

formyl-CoA + H₂O ${\displaystyle \rightleftharpoons }$ CoA + formate

This enzyme belongs to the family of hydrolases, specifically those acting on thioester bonds. The systematic name is formyl-CoA hydrolase. This enzyme is also called formyl coenzyme A hydrolase. This enzyme participates in glyoxylate and dicarboxylate metabolism.

References

• Sly WS, Stadtman ER (August 1963). "Formate metabolism. I. Formyl coenzyme A, an intermediate in the formate-dependent decomposition of acetyl phosphate in Clostridium kluyveri". The Journal of Biological Chemistry. 238: 2632–8. PMID 14063284.