Jokisch was called up to the majors for the first time on September 2, 2014.[6]
Miami Marlins
On April 13, 2016, Jokisch was claimed off waivers by the Miami Marlins.[6] After one start for the Double–A Jacksonville Suns, he made 18 appearances for the Triple–A New Orleans Zephyrs, posting a 2.64 ERA with 19 strikeouts in 30+2⁄3 innings pitched. Jokisch was designated for assignment on July 6 following the promotion of Don Kelly.[7] He cleared waivers and was sent outright to Double–A Jacksonville on July 8.[8]
Texas Rangers
On July 8, 2016, the Marlins traded Jokisch to the Texas Rangers in exchange for Pedro Ciriaco. As he had been outrighted the same day, Jokisch did not occupy a spot on Texas' 40-man roster.[9] In 7 games (4 starts) for the Triple–A Round Rock Express, he logged a 4.13 ERA with 15 strikeouts over 24 innings of work. Jokisch elected free agency following the season on November 7.[10]
Arizona Diamondbacks
On February 26, 2017, Jokisch signed a minor league contract with the Arizona Diamondbacks organization.[11] Jokisch spent the 2017 season with the Triple–A Reno Aces, also making 1 start for the Double–A Jackson Generals. In 28 games (21 starts) for Reno, he logged an 8–8 record and 4.21 ERA with 91 strikeouts in 134+2⁄3 innings pitched. He elected free agency following the season on November 6, 2017.[12]
Oakland Athletics
On December 7, 2017, Jokisch signed a minor league contract with the Oakland Athletics organization.[13] He spent the 2018 season with the Triple–A Nashville Sounds, making 26 appearances (23 starts) and registering a 5–11 record and 4.06 ERA with 121 strikeouts in 148+2⁄3 innings of work.[14] Jokisch elected free agency after the season on November 2, 2018.[15][6]
Kiwoom Heroes
On November 23, 2018, Jokisch signed a one-year, $500,000 contract with the Kiwoom Heroes of the KBO League.[16] He produced a 13–9 record with a 3.13 ERA over 181.1 innings in 2019. Jokisch re-signed with Kiwoom for the 2020 season on a one-year contract worth $700,000.[17] In 2020 Jokisch led the team with 159.2 innings with an ERA of 2.14 ,winning the league’s ERA title. He re-signed with the Heroes on a one year $900k deal for the 2021 season on December 2, 2020.[18] Jokisch tied for the league lead in wins (16), while ranking second in innings pitched (181+1⁄3) and fourth in ERA (2.93).
On December 30, 2021, he re-signed with the Heroes on a one-year deal worth up to $1.3 million.[19] Jokisch started 30 games for Kiwoom in 2022, registering a 10–8 record and 2.57 ERA with 154 strikeouts across a career–high 185+2⁄3 innings pitched. On December 11, 2022, Jokisch re-signed a one-year contract worth $1.5 million. He would make 12 starts for the team in 2023, logging a 5–3 record and 4.39 ERA with 51 strikeouts in 65+2⁄3 innings of work. In early June, Jokisch suffered a tear in his left adductor muscle and was ruled out for six weeks. Rather than wait for Jokisch to get healthy, the Heroes released him on June 16 and signed Ian McKinney.[20]