Elephantopus scaber is used as a traditional medicine.[9] Different parts of the plant are used in traditional medicine of India as an astringent agent, cardiac tonic, and diuretic, and is used for eczema, rheumatism, fever, and bladder stones.[10]E. scaber modulates inflammatory responses by inhibiting the production of TNFα and IL-1β.[11]
Chemical constituents
Elephantopus scaber contains elephantopin which is a germacranolidesesquiterpene lactone containing two lactone rings and an epoxide functional group.[12][13] 17,19-Dihydrodeoxyelephantopin, iso-17,19- dihydro-deoxy elephantopin and 8-hydroxyl
naringenin are the most important bioactive compounds responsible for anti-bacterial activity.[citation needed] By UPLC MS Q-TOF, 34 components were identified.[11]
^Jeffrey, C. 1988. Notes on Compositae: V. The Vernonieae in East Tropical Africa. Kew Bulletin 43(2): 195–277.
^Nelson, C. H. 2008. Catálogo de las Plantas Vasculares de Honduras 1–1576. Secretaria de Recursos Naturales y Ambiente, Tegucigalpa.
^Poli, A; Nicolau, M; Simoes, Cm; Nicolau, Rm; Zanin, M (Aug 1992). "Preliminary pharmacologic evaluation of crude whole plant extracts of Elephantopus scaber. Part I: in vivo studies". Journal of Ethnopharmacology. 37 (1): 71–6. doi:10.1016/0378-8741(92)90005-C. ISSN0378-8741. PMID1453704.
^ abAbhimannue, Anu P.; Mohan, Mohind C.; B, Prakash Kumar (13 February 2016). "Inhibition of Tumor Necrosis Factor-α and Interleukin-1β Production in Lipopolysaccharide-Stimulated Monocytes by Methanolic Extract of Elephantopus scaber Linn and Identification of Bioactive Components". Applied Biochemistry and Biotechnology. 179 (3): 427–443. doi:10.1007/s12010-016-2004-0. PMID26875087. S2CID7097943.