Nedelcu started his senior career at Viitorul Constanța, for which he made his debut at age 17. He aided the side in winning its first national championship in the 2016–17 season, before being transferred to fellow league team FCSB.
Internationally, Nedelcu earned his first cap for Romania in November 2016, in a 0–1 loss to Russia. He represented the under-21 team at the 2019 UEFA European Championship, where they managed to progress to the semi-finals as group winners.
On 10 August 2017, Nedelcu signed a five-year contract with FCSB,[2][3] one month after having initially refused to do so by arguing that he dreams of playing abroad.[4] Him and his Viitorul teammate Romario Benzar were acquired by the Bucharest-based club for a combined cost of €2.7 million,[5] and an additional €500,000 fee was paid for Nedelcu in November to remove an interest clause in his deal.[6]
Nedelcu made his debut for the Roș-albaștrii in a 1–1 league draw with Astra Giurgiu on 12 August 2017.[7] On 5 November that year, he scored his first goal in a 2–1 victory over Concordia Chiajna.[8]
Loans to Fortuna Düsseldorf and Farul Constanța
Nedelcu often struggled with injuries during his stint in the capital, and on 12 June 2021 was sent out on a one-year loan with a purchase option to 2. Bundesliga club Fortuna Düsseldorf.[9] On 4 February 2022, after his loan at Fortuna was cancelled prematurely, he moved to his boyhood club Viitorul—now renamed Farul Constanța—on loan for the remainder of the campaign.[10]
Farul Constanța
On 14 June 2022, Nedelcu moved to Farul Constanța on a permanent basis after signing a three-year contract.[11]
^"Bine ai (re)venit, Dragoș Nedelcu !" [Welcome back (again) Dragoș Nedelcu!] (in Romanian). FCV Farul Constanța. 4 February 2022. Retrieved 4 February 2022.