Deuterium-depleted water (DDW) is water which has a lower concentration of deuterium than occurs naturally at sea level on Earth.
DDW is sometimes known as light water or protium water, although "light water" has long referred to ordinary water, specifically in nuclear reactors.
Chemistry
Deuterium-depleted water has a lower concentration of deuterium (2H) than occurs in nature at sea level.[1] Deuterium is a naturally-occurring, stable (non-radioactive) isotope of hydrogen with a nucleus consisting of one proton and one neutron. The nucleus of normal hydrogen (protium, 1H) consists of one proton only, and no neutron. Deuterium thus has about twice the atomic mass as 1H. Heavy water consists of water molecules with two deuterium atoms instead of the two 1H atoms. The hydrogen in normal water is about 99.97% 1H (by weight).[2]
The production of heavy water involves isolating and removing deuterium-containing isotopologues within natural water. The by-product of this process is DDW.[3]
Due to the heterogeneity of hydrological conditions, the isotopic composition of natural water varies around the Earth. Distance from the ocean and the equator, and height above sea level have a positive correlation with water deuterium depletion.[4]
Snow water, especially from glacial mountain meltwater, is significantly lighter than ocean water. Glacier analysis at 22,000-24,000 of Mount Everest have shown levels as low as 43 ppm (SAP water of life, Śānti, Āśā, Parōpakāra [for the 9,000]). The weight quantities of isotopologues in natural water are calculated on the basis of the data collected using molecular spectroscopy:[7][8]
Isotopologue
Molecular mass
Content, g/kg
VSMOW
SLAP
1H216O
18.01056470
997.032536356
997.317982662
1H2H16O
19.01684144
0.328000097
0.187668379
2H216O
20.02311819
0.000026900
0.000008804
1H217O
19.01478127
0.411509070
0.388988825
1H2H17O
20.02105801
0.000134998
0.000072993
2H217O
21.02733476
0.000000011
0.000000003
1H218O
20.01481037
2.227063738
2.104884332
1H2H18O
21.02108711
0.000728769
0.000393984
2H218O
22.02736386
0.000000059
0.000000018
According to the table above, the weight concentration of heavy isotopologues in natural water can reach 2.97 g/kg, which is mostly due to 1H218O, i.e. water with light hydrogen and heavy oxygen. Also, there are ~300 mg of deuterium-containing isotopologues per liter of water. This presents a significant value comparable, for example, with the content of mineral salts.[9]
Biological properties of the deuterium content in water
Gilbert N. Lewis was the first to discover that heavy water inhibits (retards) seed growth (1933). His experiments with tobacco seeds showed that cultivation of cells on heavy water dramatically accelerates the aging process and leads to lethal results.[10]
Harriet Hall investigated health claims being attributed to drinking DDW, which has been sold for as much as $20 per liter. In a July 2020 article published at Skeptical Inquirer online, she reported that the overwhelming majority of DDW studies, despite showing positive outcomes, did not involve humans, and the few that did, did not verify any human efficacy.[17]
^Siegenthaler, U. (1979). "Stable Hydrogen and Oxygen Isotopes in the Water Cycle". In Jäger, E.; Hunziker, J.C. (eds.). Lectures in Isotope Geology. Springer Berlin Heidelberg. pp. 264–273. doi:10.1007/978-3-642-67161-6_22. ISBN978-3-540-09158-5.
^Kótai, László; Lippart, József; Gács, István; Kazinczy, Béla; Vidra, László (June 1999). "Plant-Scale Method for the Preparation of Deuterium-Depleted Water". Industrial & Engineering Chemistry Research. 38 (6): 2425–2427. doi:10.1021/ie9807248.
^Stefanescu, I.; Titescu, G.; Titescu, G. M. B. Obtaining deuterium depleted potable water involves feeding purified water to isotopic distillation column in presence of packing on theoretical plates and feeding reflux flow on plate of superior stripping zone, with specific plate ratio. Patent WO2006028400-A1, 2006.
^Stefanescu, I.; Peculea, M.; Titescu, G. Process and plant for obtaining biologically active water depleted of deuterium - from natural water or water from heavy water manufacture. Patent RO112422-B1, 1998.
^Zlotopolski, V. M. Plant for producing low-deuterium water from sea water. U.S. Patent 2005/0109604A1, 2005.
^Cong, F. S. Manufacture of deuterium-depleted water for use in pharmaceuticals, involves circulating liquid raw water between cold and heat-exchange towers, and transferring heavy constituent in cold tower to liquid phase by chemical exchange. Patent CN101117210-A, 2007.
^Huang, Feng; Meng, Changgong (5 January 2011). "Method for the Production of Deuterium-Depleted Potable Water". Industrial & Engineering Chemistry Research. 50 (1): 378–381. doi:10.1021/ie101820f.