Born in Brixen, South Tyrol, Karbon made her World Cup debut in 1998 at age 17, while the following year she was Junior World Champion. She won a total of six World Cup giant slaloms: in December 2003 at Alta Badia and five of the first six races in the 2008 season. She obtained ten other podiums for a total of sixteen.
Karbon won a silver medal at the 2003 World Championships in giant slalom, followed by a bronze in 2007 in the same discipline.
In the 2008 season, Karbon won 5 of the 7 giant slalom races (and took third in another) to win the GS season title with 592 points, 113 points ahead of runner-up Elisabeth Görgl. She finished tenth in the overall standings.
At age 33, Karbon retired in March 2014, after the World Cup finals in Lenzerheide.[1]