Crich began his independent career in 1985 when he took up a lectureship in chemistry in the Christopher Ingold Laboratories at University College London (UCL) in London. After five years at UCL, Crich moved to the University of Illinois (UIC) in Chicago where he rose through the ranks to become Distinguished Professor of Organic Chemistry. It was at UIC where Crich discovered the Crich beta-mannosylation reaction. In 2007, Crich relocated to Wayne State University in Detroit as the Schaap Professor of Chemistry, before returning to the ICSN, where he was appointed the institute's director. Crich returned to Wayne State as the Schaap Professor in 2011 and stayed there until 2019 when he moved to the University of Georgia as the Georgia Research Alliance and David Chu Eminent Scholar in Drug Design.[7]
Awards and honors
Academia des Sciences / Royal Society, Franco-British Prize (1989)
Royal Society of Chemistry, Corday-Morgan Medal (1990)
University of Illinois, University Scholar (1992)[8]
Fellow of the A. P. Sloan Foundation (1994)
Royal Society of Chemistry, Carbohydrate Chemistry Award (1994)[9]
Electronic Encyclopedia of Reagents for Organic Synthesis, Executive Editor (2002–2009)
Fellow of the Japan Society for the Promotion of Science (2006)
Honorary Doctor of Science, University of Derby (2007)[10]
American Chemical Society, Wolfram Award (2008)[11]
Electronic Encyclopedia of Reagents for Organic Synthesis, Editor in Chief (2009–2015)
American Chemical Society, Arthur C Cope Senior Scholar (2011)[12]
European Carbohydrate Society, Emil Fischer Award (2011)[13]
Royal Society of Chemistry, Haworth Memorial Lecturer and Medal (2014)[14]
American Chemical Society, C. S. Hudson Award (2017)[15]
International Carbohydrate Organization, Whistler Prize (2018)[16]
American Chemical Society, James Flack Norris Award in Physical Organic Chemistry (2024)[17]
National Academy of Inventors, Senior Member (2024)[18]
^Barton, D. H. R.; Crich, D.; Motherwell, W. B. (1985). "The invention of new radical chain reactions. Part VIII. Radical chemistry of thiohydroxamic esters; A new method for the generation of carbon radicals from carboxylic acids". Tetrahedron Letters. 41 (19): 3901. doi:10.1016/S0040-4020(01)97173-X.