Coumarinolignoid

Aleuritin, a coumarinolignoid found in Aleurites fordii.

Coumarinolignoids are a class of phenolic compounds. They are a subset of lignans in which one of the two phenylpropanoids is found in the form of a coumarin.

Examples

• 2-(4-hydroxy-3,5-dimethoxyphenyl)-3-hydroxymethyl-2,3-dihydro-1,4,5-trioxaphenanthren-6-one can be found on Paullinia pinnata
• 5'-hydroxycleomiscosin B, found in Eurycorymbus cavaleriei[1]
• 5-Methoxypropacin found in Protium unifoliolatum[2]
• Moluccanin, found in Aleurites moluccanus,[3] synthesised by Kim et al in 2023.[4]
• Aleuritin, found in Aleurites fordii[5]
• Durantin A and repenins, isolated from Duranta

References

1. Ma, Zhongjun; Zhang, Xiaoyu; Cheng, Lin; Zhang, Peng (2009). "Three lignans and one coumarinolignoid with quinone reductase activity from Eurycorymbus cavaleriei". Fitoterapia. 80 (6): 320–6. doi:10.1016/j.fitote.2009.04.003. PMID 19376206.
2. Magalhães, A; Zoghbi, MD; Siani, AC (2006). "5-Methoxypropacin, a novel coumarinolignoid from Protium unifoliolatum". Natural Product Research. 20 (1): 43–6. doi:10.1080/14786410500055555. PMID 16286307. S2CID 38930950.
3. Shamsuddin, T.; Rahman, W.; Khan, Suroor A.; Shamsuddin, K.M.; Kintzinger, J. (1988). "Moluccanin, a coumarinolignoid from Aleurites moluccana". Phytochemistry. 27 (6): 1908. doi:10.1016/0031-9422(88)80480-1.
4. Kim, Irene Jeongin; Pilkington, Lisa I.; Barker, David (2023-05-05). "Total Synthesis of Linear Coumarniolignoids (+) and (−)-Sapiumin C, (−)-Moluccanin, and (−)-Hemidesminine". The Journal of Organic Chemistry. 88 (9): 5900–5912. doi:10.1021/acs.joc.3c00292. hdl:2292/64128. ISSN 0022-3263. PMID 37071826. S2CID 258214382.
5. Fozdar, B.I.; Khan, Suroor A.; Shamsuddin, T.; Shamsuddin, K.M.; Kintzinger, J. (1989). "Aleuritin, a coumarinolignoid, and a coumarin from Aleurites fordii". Phytochemistry. 28 (9): 2459. doi:10.1016/S0031-9422(00)98005-1.