The winner of Group C, Mexico, advanced to play the runner-up of Group D, Chile.
The runner-up of Group C, Venezuela, advanced to play the winner of Group D, Argentina.
Matches
Jamaica vs Venezuela
The two teams had met in six previous occasions, all of them being friendlies. Their last encounter was on March 27, 2015 at the Montego Bay Sports Complex, which Jamaica won 2–1.
The two teams had met in eighteen previous occasions, the latest being the 2015 CONCACAF Gold Cup Final, won by Mexico 3–1. This marked the first time both teams faced each other in a competitive match outside of CONCACAF official competitions.
The two teams had met in ten previous occasions, the latest being a friendly played in 2012, which Mexico won 3–1. The friendly was held at the NRG Stadium, the same venue of this Copa América Centenario encounter. Their last Copa América meeting was a 1999 group stage match, also won by Mexico 3–1.
The two teams had met in four previous occasions, the last being Jamaica's debut in the previous year's Copa América, which Uruguay won with a lone goal scored by Cristian Rodríguez.