en Complement receptor of the immunoglobulin family

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Structures	Swiss-model
Domains	InterPro

V-set and immunoglobulin domain containing 4
V-set and immunoglobulin domain containing 4
Identifiers
Symbol	VSIG4
NCBI gene	11326
HGNC	17032
OMIM	300353
RefSeq	NM_007268
UniProt	Q9Y279
Other data
Locus	Chr. X q12-q13.3
Structures
Search for
Structures	Swiss-model
Domains	InterPro

Complement receptor of the immunoglobulin family is a protein expressed in Kupffer cells.^[1] It is a critical receptor for the phagocytosis of opsonised particles in the blood. It recognizes iC3b (inactivated C3b) deposited on microbial surfaces.

References

^ Helmy K, Katschke K, Gorgani N, Kljavin N, Elliott J, Diehl L, Scales S, Ghilardi N, van Lookeren Campagne M (2006). "CRIg: a macrophage complement receptor required for phagocytosis of circulating pathogens". Cell. 124 (5): 915–27. doi:10.1016/j.cell.2005.12.039. PMID 16530040.

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[1] Helmy K, Katschke K, Gorgani N, Kljavin N, Elliott J, Diehl L, Scales S, Ghilardi N, van Lookeren Campagne M (2006). "CRIg: a macrophage complement receptor required for phagocytosis of circulating pathogens". Cell. 124 (5): 915–27. doi:10.1016/j.cell.2005.12.039. PMID 16530040.

[1]

Complement receptor of the immunoglobulin family

See also

References