Christopher Chang

Christopher J. Chang
Born	1974 (age 49–50) Ames, Iowa, U.S.
Alma mater	California Institute of Technology (BS, MS) Massachusetts Institute of Technology (PhD)
Spouse	Michelle Chang
Awards	ACS Cope Scholar Award (2010) Sackler Prize in Chemistry (2019)
Scientific career
Fields	Chemistry
Institutions	UC Berkeley Princeton University
Thesis	Small-molecule activation chemistry catalyzed by proton-coupled electron transfer (2002)
Doctoral advisor	Daniel G. Nocera
Other academic advisors	Harry B. Gray, Jean-Pierre Sauvage, Stephen J. Lippard
Notable students	Hemamala Karunadasa
Website	chrischang.chemistry.princeton.edu

Christopher J. Chang is an American chemist and the Edward and Virginia Taylor Professor of Bioorganic Chemistry at Princeton University. Previously, he was a professor of chemistry and of molecular and cell biology at the University of California, Berkeley, where he holds the Class of 1942 Chair.[1] Chang is also a member of the Helen Wills Neuroscience Institute, a Howard Hughes Medical Institute investigator, adjunct professor of pharmaceutical chemistry at the University of California, San Francisco, and faculty scientist at the chemical sciences division of Lawrence Berkeley Lab.[1][2] He is the recipient of several awards for his research in bioinorganic chemistry, molecular and chemical biology.[3]

His research interests include molecular imaging sensors for the study of redox biology[4][5] and metals,[6] especially as applied to neuroscience and immunology, metal catalysts for renewable energy cycles, and green chemistry.[1]

Early life and education

Chang was born in 1974 in Ames, Iowa, and was raised in Indiana.[1][7] He attended the California Institute of Technology for his undergraduate degree, where he studied chemistry. At Caltech, he worked with Harry B. Gray on the synthesis and characterization of metal salen complexes of manganese and vanadium, and nitrogen and oxygen transfer reactivity with these complexes, respectively.[8][9][10] Chang earned his BS and MS in chemistry in 1997, after which he worked in the laboratory of Jean-Pierre Sauvage at the Université Louis Pasteur as a Fulbright Fellow. In 1999, he moved to the Massachusetts Institute of Technology as a NSF/Merck Graduate Fellow. During his doctoral studies, Chang worked in the laboratory of Daniel G. Nocera. After earning his PhD in inorganic chemistry in 2002, Chang remained at MIT, working with Stephen J. Lippard as a Jane Coffin Childs Fellow.

Independent career

In 2004, Chang began his independent career as an assistant professor of chemistry at the University of California, Berkeley. He was promoted to associate professor in 2009, and full professor of chemistry in 2012, when he was also appointed professor of molecular and cell biology and co-director, chemical biology graduate program.[1] In 2024, he joined the faculty at Princeton University.[11]

Awards

• Davison Thesis Prize (Massachusetts Institute of Technology, 2003) [12]
• Camille and Henry Dreyfus Foundation New Faculty Award (2004) [12]
• Arnold and Mabel Beckman Foundation Beckman Young Investigators Award (2005) [12]
• American Federation for Aging Research Award (2005) [12]
• David and Lucile Packard Foundation Fellow[13]
• National Science Foundation CAREER Award (2006) [12]
• Paul Saltman Award, Metals in Biology GRC (2008) [12]
• Amgen Young Investigator Award (2008) [12]
• Hellman Faculty Award (2008)[14]
• Bau Award in Inorganic Chemistry, Chinese Academy of Sciences (2008) [12]
• TR35: Technology Review magazine Young Innovator Award (2008)[15]
• Astra Zeneca Excellence in Chemistry Award (2009) [12]
• Novartis Young Investigator Award in Organic Chemistry (2009) [12]
• Donald Sterling Noyce Prize for Excellence in Undergraduate Teaching (2013)
• Blavatnik Award for Young Scientists (2015)[16]
• Elected to the American Academy of Arts and Sciences (2017)[17]
• Humboldt Research Award (2020)[18]
• Guggenheim Fellowship (2021)[19][20][21]

Personal life

Christopher is married to his colleague in the department of chemistry, Michelle Chang.[7][22]

References

1. "Christopher J. Chang". College of Chemistry, University of California, Berkeley. Retrieved May 29, 2021.
2. "Christopher J. Chang – Chemical Sciences Division Chemical Sciences Division". commons.lbl.gov. Retrieved May 29, 2021.
3. "Chang Group – Homepage". Cchem.berkeley.edu. Retrieved May 6, 2015.
4. Miller, Evan W.; Tulyathan, Orapim; Isacoff, Ehud Y.; Chang, Christopher J. (2007). "Molecular imaging of hydrogen peroxide produced for cell signaling : Abstract : Nature Chemical Biology". Nature Chemical Biology. 3 (5): 263–267. doi:10.1038/nchembio871. PMID 17401379.
5. Dickinson, Bryan C.; Chang, Christopher J. (2008). "A Targetable Fluorescent Probe for Imaging Hydrogen Peroxide in the Mitochondria of Living Cells". Journal of the American Chemical Society. 130 (30): 9638–9639. doi:10.1021/ja802355u. PMC 2810491. PMID 18605728.
6. Domaille, Dylan W.; Zeng, Li; Chang, Christopher J. (2010). "Visualizing Ascorbate-Triggered Release of Labile Copper within Living Cells using a Ratiometric Fluorescent Sensor". Journal of the American Chemical Society. 132 (4): 1194–1195. doi:10.1021/ja907778b. PMC 2819030. PMID 20052977.
7. "Christopher Chang". American Chemical Society. Retrieved May 29, 2021.
8. Chang, Christopher J.; Low, Donald W.; Gray, Harry B. (1997). "Reversible Nitrogen Atom Transfer between Nitridomanganese(V) and Manganese(III) Schiff-Base Complexes". Inorganic Chemistry. 36 (3): 270–271. doi:10.1021/ic961023a. ISSN 0020-1669.
9. Chang, Christopher J.; Connick, William B.; Low, Donald W.; Day, Michael W.; Gray, Harry B. (1998). "Electronic Structures of Nitridomanganese(V) Complexes". Inorganic Chemistry. 37 (12): 3107–3110. doi:10.1021/ic970598k. ISSN 0020-1669.
10. Chang, Christopher J.; Labinger, Jay A.; Gray, Harry B. (December 1, 1997). "Aerobic Epoxidation of Olefins Catalyzed by Electronegative Vanadyl Salen Complexes". Inorganic Chemistry. 36 (25): 5927–5930. doi:10.1021/ic970824q. ISSN 0020-1669. PMID 11670216.
11. "Christopher Chang Joins Princeton Chemistry – Princeton University Department of Chemistry". chemistry.princeton.edu. Retrieved December 20, 2024.
12. "Faculty & Research | College of Chemistry". Chem.berkeley.edu. Retrieved May 6, 2015.
13. "Chang, Christopher". The David and Lucile Packard Foundation. Retrieved May 29, 2021.
14. "Hellman Fellows » Christopher Chang". Retrieved May 29, 2021.
15. "Innovator Under 35: Christopher Chang, 33". MIT Technology Review. Retrieved May 29, 2021.
16. "2015 National Laureates". New York Academy of Sciences. Retrieved December 4, 2015.
17. "Christopher J. Chang". American Academy of Arts & Sciences. Retrieved May 29, 2021.
18. "Berkeley Professor Christopher J. Chang to stay at MPIMR after being awarded the Humboldt Research Award". www.mr.mpg.de. Retrieved May 29, 2021.
19. "Christopher J. Chang". John Simon Guggenheim Foundation. Retrieved May 29, 2021.
20. Ati, Shylie (April 15, 2021). "4 UC Berkeley faculty receive Guggenheim Fellowship". The Daily Californian. Retrieved May 29, 2021.
21. "Guggenheim Fellowship awarded to Christopher Chang". College of Chemistry, University of California, Berkeley. Retrieved May 29, 2021.
22. "National magazines tout two chemists and two astronomers as top innovators in their fields", UC Berkeley News, August 22, 2008 (retrieved December 12, 2014)