Somerville was co-founder and Executive Chairman of Mendel Biotechnology, Inc. and a co-founder of Poetic Genetics, LS9, Inc, and Redleaf Biologics.[4]
Somerville has contributed to societal debates on the value of transgenic crops[5] and biofuels.
Together with Elliot Meyerowitz, Somerville was awarded the Balzan Prize in 2006 for his work developing the small mustard plant A. thaliana as a model.[6][1][7][8] His interest in this plant was partly stimulated by a review article[9] written by George Rédei.[10][2][11]
Many trainees from Somerville's lab have started independent labs, including Mark Estelle, Peter McCourt, George W. Haughn, John W. Schiefelbein, Christoph Benning, Clint Chapple, Wolf-Dieter Reiter, John Browse, Sean Cutler, Dominique Bergmann, Seung Y. Rhee, Staffan Persson, Wolfgang Lukowitz, C. Stewart Gillmor, Jose Martinez-Zapater, Hong Zhang, Ruth Finkelstein, Micha Volokita, Barbara Moffatt, Kathy Wu, Jose Botella, Bertrand Lemieux, Erwin Grill, John Shanklin, Yves Poirier, Christianne nawrath, Susan Gibson, Deane Falcone, Koh Iba, Simon Turner, Pierre Broun, Sean Cutler, Joe Ogas, Wolf Scheible, Dario Bonetta, John Sedbrook, Heather Youngs, Farhah Assaad, Michelle Facette, Alex Paredez, Jose Estevez, Seth DeBolt, Thorsten Hamman, Ying Gu, Ian Wallace, Philipp Benz, Charles Anderson, and Adrienne Roeder.
Estelle, M. A.; Somerville, Chris R. (1986). "The mutants of Arabidopsis". Trends in Genetics. 2: 89–93. doi:10.1016/0168-9525(86)90190-3.
Somerville, Chris; Koornneef, Maarten (2002). "A fortunate choice: the history of Arabidopsis as a model plant". Nature Reviews Genetics. 3 (11): 883–889. doi:10.1038/nrg927. PMID12415318. S2CID37515057.
Youngs, Heather; Somerville, Chris (2017-06-01). "Implementing industrial–academic partnerships to advance bioenergy research: the Energy Biosciences Institute". Current Opinion in Biotechnology. 45: 184–190. doi:10.1016/j.copbio.2017.03.027. PMID28458111.
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Arondel, V.; Lemieux, B.; Hwang, I.; Gibson, S.; Goodman, H. M.; Somerville, C. R. (1992-11-20). "Map-based cloning of a gene controlling omega-3 fatty acid desaturation in Arabidopsis". Science. 258 (5086): 1353–1355. Bibcode:1992Sci...258.1353A. doi:10.1126/science.1455229. PMID1455229.