Sanders was hired on January 29, 2009, by the Buffalo Bills as defensive line coach.[2] He was dismissed, along with the entire Bills coaching staff on December 31, 2012.[3] Sanders worked under Steve Spurrier for 11 years at Florida. He also worked at Miami under the veteran defensive coordinator Jim Bates for five years, from 2001 to 2004 coaching linebackers and, in 2005, as defensive ends coach in Green Bay.
On February 2, 2015, it was announced that Sanders had been hired as the linebackers coach with the Arizona Cardinals.
In 2019, Sanders reunited with Spurrier as the defensive coordinator of the Apollos.[4]
On March 1, 2022, Sanders reunited with Arians as the outside linebackers coach for the Tampa Bay Buccaneers.[5]