Benzomorphan

Benzomorphan

Names
IUPAC name 6,7-Benzomorphan
Other names 1,2,3,4,5,6-Hexahydro-2,6-methano-3-benzazocine< 10-Azatricyclo[7.3.1.0~2,7~]trideca-2,4,6-triene
Identifiers
CAS Number	575-19-9^Y
3D model (JSmol)	Interactive image
ChemSpider	158637^N
PubChem CID	182394
UNII	A8J3S2MS1D^Y
CompTox Dashboard (EPA)	DTXSID80982138
InChI InChI=1S/C12H15N/c1-2-4-12-9(3-1)7-11-8-10(12)5-6-13-11/h1-4,10-11,13H,5-8H2^N Key: NSLKFRGZLUIUKO-UHFFFAOYSA-N^N InChI=1/C12H15N/c1-2-4-12-9(3-1)7-11-8-10(12)5-6-13-11/h1-4,10-11,13H,5-8H2 Key: NSLKFRGZLUIUKO-UHFFFAOYAF
SMILES C1CNC2CC1C3=CC=CC=C3C2
Properties
Chemical formula	C12H15N
Molar mass	173.259 g·mol^−1
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa). N verify (what is ^YN ?) Infobox references

Benzomorphan is a chemical compound that is the base for a series of drugs which variably act on the sigma receptors and κ-opioid receptors, including the following compounds:

• 5,9-DEHB
• 8-CAC
• Alazocine
• Anazocine
• Bremazocine
• Butinazocine
• Carbazocine
• Cogazocine
• Cyclazocine
• Dezocine
• Eptazocine
• Etazocine
• Ethylketocyclazocine
• Fluorophen
• Gemazocine
• Ibazocine
• Ketazocine
• Metazocine
• Moxazocine
• Pentazocine
• Phenazocine
• Quadazocine
• Thiazocine
• Tonazocine
• Volazocine
• Zenazocine

Some of these agents are used as analgesics, including pentazocine, phenazocine, dezocine, and eptazocine.[1][2]

See also

• Benzazocine
• Azocine
• Morphinan

References

1. Kar, Ashutosh (2005). Medicinal Chemistry - Google Books. ISBN 9788122415650.
2. Cittern PA, Kapoor VK, Parfitt RT (October 1986). "Preparation and analgesic activity of (−)-11 alpha-substituted 1,2,3,4,5,6-hexahydro-6 alpha,7-(methyleneoxy)-2,6-methano-3-benzazocines". Journal of Medicinal Chemistry. 29 (10): 1929–33. doi:10.1021/jm00160a022. PMID 2876100.