The station opened in 1869 with the opening of the Randers-Aalborg railway line from Randers to Aalborg.[3][4] The original villages in the area were Hesselholt a little west of the station, Store Arden a little east of the station and Lille Arden further east. After the opening of the railway line, a railway town quickly developed around the station. The name Arden for the railway town only arose later, and on maps of the town Arden was not used, Store Arden or Hesselholt being used instead.[5]
The station survived a series of station closures in the 1970s.[3]