*Club domestic league appearances and goals, correct as of 23:44, 28 September 2024 (UTC) ‡ National team caps and goals, correct as of 9 September 2024
Cambiaso returned to Genoa for the 2021–22 season, scoring his first goal in Serie A on 29 August 2021 in a 2–1 home defeat against Napoli.[2]
Loan moves to Alessandria and Empoli
On 2 August 2019, Cambiaso joined Serie C club Alessandria on loan.[3] He made his professional Serie C debut for Alessandria on 25 August 2019 in the opening game against Gozzano, starting the game and playing the whole match.[4] Cambiaso suffered an ACL tear on 4 December 2019 in a match against Juventus U23 (which was his 17th start for the club), the injury would keep him unable to play for the rest of the 2019–20 season.[5]
On 21 September 2020, he joined Serie B club Empoli on loan with an option to purchase.[6]
Juventus
On 14 July 2022, Juventus announced the signing of Cambiaso on a five-year contract.[7] The following day, Cambiaso joined Bologna on a season-long loan.[8]
On 28 October 2023, he scored his first goal for Juventus in the sixth minute of stoppage time in a 1–0 victory over Hellas Verona.[9] On 15 May 2024, Cambiaso started in the Coppa Italia final as Juventus defeated Atalanta by a score of 1–0 to lift the trophy for a record-extending 15th time.[10] On 24 May, he extended his contract with the club until 2029.[11]