Lioi played for Renato Cesarini in his youth career before joining Rosario Central, signing his first professional contract with them in November 2017.[3][4] He was promoted into the first-team midway through the 2017–18 season, making his professional debut on 24 January 2018 in a 1–1 draw with Independiente.[1][5] Four appearances later, on 17 February, Lioi scored a hat-trick during a 5–0 league win at the Estadio Gigante de Arroyito against Olimpo.[1][6] After twenty-eight matches across two campaigns for Rosario, Lioi departed on loan on 13 August 2019 to Polish Ekstraklasa outfit Korona Kielce.[7]
After making twelve appearances for Korona, as well as five outings for their reserve team, Lioi's loan was extended until July - from 30 June - after the end of the 2019–20 campaign was delayed due to the COVID-19 pandemic.[1][8]