Amplification is a judged tendency of a person to amplify physical symptoms based on negative psychological factors such as anxiety or depression. A distinct interpretation of amplification could be sensory processing disorder involving differences in the way a person reacts to sensory input, a symptom associated autism spectrum disorder.[1] An indicidual’s psychological state has been documented to affect the course of upper respiratory tract infection,[2][3] post-infectious irritable bowel syndrome,[4] and musculoskeletal pain.[5] Amplification is not recognized by the American Psychiatric Association.
Amplification is related to alexithymia.[6][7] Amplification may also contribute to multiple-drug intolerance (if the adverse effects that are reported are non-specific).[8] It is unclear whether amplification is related to observations that Type A personality traits may be associated with delayed recovery after organic illness.[9][10]
Assessment
The somatosensory amplification scale (SSAS) has been validated to measure amplification.[1] The scale contains four items measured with a five-item Likert scale:
Sudden loud noises really disturb me
I'm very uncomfortable when I'm in a place that is too hot or too cold
I can't stand pain as well as most people can
I find I'm often aware of various things happening in my body
I'm quick to sense the hunger contractions in my stomach
^IMBODEN JB, CANTER A, CLUFF LE (1961). "Convalescence from influenza. A study of the psychological and clinical determinants". Arch. Intern. Med. 108: 393–9. doi:10.1001/archinte.1961.03620090065008. PMID13717585.
^Lane RS, Barsky AJ, Goodson JD (1988). "Discomfort and disability in upper respiratory tract infection". Journal of General Internal Medicine. 3 (6): 540–6. doi:10.1007/BF02596095. PMID3230456. S2CID28428075.
^Fields KB, Delaney M, Hinkle JS (1990). "A prospective study of type A behavior and running injuries". The Journal of Family Practice. 30 (4): 425–9. PMID2324695.