Albert Gjedde:[1][2][3] is a Danish-Canadian neuroscientist. He is Professor of Neurobiology and Pharmacology at the Faculty of Health Sciences and Center of Neuroscience at the University of Copenhagen. He is currently also Adjunct Professor of Neurology and Neurosurgery in the Department of Neurology, Montreal Neurological Institute, McGill University, Montreal, Quebec, Canada, Adjunct Professor of Radiology and Radiological Science in the Division of Nuclear Medicine, Department of Radiology and Radiological Science, Johns Hopkins University, Baltimore, Maryland, US, Adjunct Professor of Translational Neuropsychiatry Research, University of Southern Denmark, Odense, Denmark, and adjunct professor of psychiatry at Tabriz University of Medical Sciences, Tabriz, East Azerbadjan, Iran.
Albert Gjedde received his Medical Doctor (M.D). and Doctor of Science (D.Sc.) degrees from Copenhagen University in 1973 and 1983, respectively. He did postdoctoral work in the Neurology Department of the New York Hospital-Cornell Medical Center 1973-76 and held assistant and associate professorships in Medical Physiology at the University of Copenhagen 1976–1986.
As a junior investigator, Albert Gjedde worked as a visiting scientist at universities or research institutions in Lund, Sweden; Cologne, Leipzig, and Dresden, Germany; Paris, France; Szeged, Hungary; and Baltimore, Maryland, United States.
In 1986 he joined the McConnell Brain Imaging Center at McGill University in Montreal where he held the post of Director between 1989 and 1994.[4]
As founder, Albert Gjedde headed the Positron Emission Tomography (PET) Center at Aarhus University Hospital in Denmark during the years 1994 to 2008,[5] and in this period he also founded the Center of Functionally Integrative Neuroscience (CFIN) in 2001[6] and the Danish Neuroscience Center (DNC) in 2008,[7][8] both at Aarhus University.
Albert Gjedde joined the University of Copenhagen in 2008. He is Fellow of the Royal Society of Canada, the American Association for the Advancement of Science, and the American College of Neuropsychopharmacology. He is also Member of the Academy of Europe, the Daylight Academy, and the Norwegian Academy of Science and Letters.
Career
Research
Albert Gjedde's research focuses on the relations between neuroplasticity and neurotransmission that can be revealed by mapping radioligand binding and the neuroplastic changes of brain functions. The investigations explore the relation between energy metabolism and neurotransmission by recording the changes of energy metabolism and consciousness under pharmacological and other manipulations. He uses PET to understand the synthesis of radioligand and tracer molecules that match the neurotransmitter molecules and the behavior of these transmitters under different functional conditions of the brain, normal as well as pathological, and the spatial and temporal relations among changes of cerebral blood flow, which is commonly used as a measure of brain work, and the cerebral oxygen consumption rate, which is the precise measure of this work. Albert Gjedde's collaborations focus on experiments with volunteer subjects and patients that explore the lesions and degeneration of brain tissue in disorders such as epilepsy, ludomania, Parkinson's disease, stroke, depression, and somatizing disorders, as well as disorders related to addiction. Experiments explore the restructuring of neuronal networks that follows when sensory activity is processed by healthy subjects or volunteers suffering from inborn or acquired lesions.
In 1977, with Clifford Patlak, Albert Gjedde described the Gjedde-Patlak plot, also known as Multitime Graphical Analysis (MTGA),.[9][10][11] The MTGA linearizes irreversible brain uptake of tracers in a manner that enables regression estimates to be made of uptake rates.
Current academic appointments
Professor of Neurobiology and Pharmacology, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark,[12] since 2008
Adjunct Professor, Department of Neurology and Neurosurgery, McGill University, Montreal, Quebec, Canada,[13] since 1994
Adjunct Professor of Radiology and Radiological Science, Johns Hopkins University, Baltimore Maryland, U.S.A.,[14] since 2006
Past academic appointments
1979–1981 Assistant Professor, Medical Physiology, The Panum Institute, University of Copenhagen, Copenhagen, Denmark
1981–1993 Associate Professor of Medical Physiology, The Panum Institute University of Copenhagen, Copenhagen, Denmark
1986–1987 Visiting Associate Professor, Montreal Neurological Institute, McGill University, Montréal, Quebec, Canada
1987–1989 Associate Professor, Department of Neurology and Neurosurgery, McGill University, Montréal, Quebec, Canada
1989–1994 Professor, Department of Neurology and Neurosurgery, McGill University, Montréal, Quebec, Canada
1989–1994 Director, McConnell Brain Imaging Center, Montreal Neurological Institute, McGill University, Montréal, Quebec, Canada[4]
1993–1994 Adjunct Professor of Human Pathophysiology, Aarhus University, Aarhus, Denmark
1993–1999 MRC (Denmark) Professor of Brain Research, Aarhus University Hospitals, Aarhus, Denmark
1994–1999 Associate Professor of Human Pathophysiology, Institute of Experimental Clinical Research, University of Aarhus, Aarhus, Denmark
1994–2008 Director and Chief Physician, Positron Emission Tomography (PET) Center, Aarhus General Hospital, Aarhus University Hospitals, Aarhus, Denmark
1999–2008 Professor of Medical Neurobiology, Faculty of Health Sciences, University of Aarhus, Aarhus, Denmark
2001–2004 Director, Centre of Functionally Integrative Neuroscience, University of Aarhus, Aarhus, Denmark
2004–2005 Visiting Professor, Department of Diagnostic Radiology, Yale School of Medicine, New Haven, CT, U.S.
2008–2014 Adjunct Professor of Neuroscience, University of Aarhus, Denmark
2008–2014 Chairman, Department of Neuroscience and Pharmacology, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark,[12] since 2008
Current academic positions
Albert Gjedde has through his career been taken different international academic positions in funding agencies, editorial- and advisory boards, council-, and committees and learned societies.[15] Today he takes following positions.
Danish National Expert and Delegate of the Horizon 2020 Programme Committee for Societal challenges (SC1), "Health, demographic change and wellbeing", EU, since 2014
1977–1979 Editorial Secretary, Volume VII (Medicine), Copenhagen University 1479–1979, volumes I-XIV, Treaties in Honor of the Quintcentennial Anniversary of Schola Hafniensis (Copenhagen University)
1987 Member, Scientific Advisory Board, XIII International Symposium on Cerebral Blood and Metabolism, Montreal, Quebec, Canada
1988–1994 Member, Scientific Advisory Board, Department of Nuclear Medicine, University of Michigan, Ann Arbor, Michigan, U.S.A.
1989–1994 Member, U.S. Department of Energy Program Grant Advisory Board, Department of Nuclear Medicine, Memorial-Sloan Kettering Cancer Center, New York, U.S.A.
1989–1994 Member, U.S. National Institutes of Health Program Grant Advisory Board, Division of Nuclear Medicine, Department of Radiology and Radiation Health Sciences, Johns Hopkins Hospital and Medical Institutions, Baltimore, Maryland, U.S.A
1989 Member, Scientific Advisory Board, XIV International Symposium on Cerebral Blood and Metabolism, Bologna, Italy
1991 Member, Scientific Advisory Board, XV International Symposium on Cerebral Blood and Metabolism, Miami, Florida, U.S.A.
1991–2006 Member, Scientific Advisory Board, Axion Research Foundation (Yale Transplant Project), Hamden, Connecticut, and Basseterre, St.Kitts, W.I.
1993 Member, Scientific Advisory Board, XVI International Symposium on Cerebral Blood and Metabolism, Sendai, Japan
2008–2010 Chairman, Gordon Research Conference on Brain Energy Metabolism and Blood Flow,
2008 Member, Organizing Committee, International Symposium on Neuroreceptor Mapping of Living Brain, Pittsburgh, Pennsylvania, U.S.A.
2008–2010 Chair, Gordon Research Conference on Brain Energy Metabolism and Blood Flow
2010 Member, Organizing Committee, International Symposium on Neuroreceptor Mapping of Living Brain, Glasgow, U.K.
2012 Member, Organizing Committee, International Symposium on Neuroreceptor Mapping of Living Brain, Baltimore, Maryland, U.S.A.
Past administrative positions
1989–1994 Director, McConnell Brain Imaging Center (BIC),[4] Montreal Neurological Institute, Canada
1994–2008 Director, Positron Emission Tomography PET Center, Aarhus University Hospital, Aarhus, Denmark
2001–2004 Director, Centre of Functionally Integrative Neuroscience (CFIN), Aarhus University
2008–2014 Head, Department of Neuroscience and Pharmacology (INF), University of Copenhagen, Denmark. Encompasses around 335 staff members, publishes around 200 peer-reviewed papers per year and has an annual budget of roughly 120 mio. DDK or 16 mio €.
2008–2014 Head, Department of Neuroscience and Pharmacology (INF), University of Copenhagen, Denmark.[12][26][27] INF encompasses around 335 staff members, publishes around 200 peer-reviewed papers per year and has an annual budget of roughly 120 mio. DDK or 160 mio €.
Academic distinctions
1970 Gold Medal in Medicine, University of Copenhagen, Denmark
Albert Gjedde has peer-reviewed, authored or edited a number of publications including the following books and booklets[43][44][45][46][47][48]
Gjedde A. (1971): Peter Ludvig Panums videnskabelige indsats. Copenhagen: Særtryk af Bibliotek for læger.[49]
Plum F, Gjedde A, Samson F (1976) (eds.) Neuroanatomical functional mapping by the radioactive 2-deoxy-D-glucose method. Neurosciences Research Program Bulletin, Boston.
Melchior JC, Andreasen E, Brøchner-Mortensen K, Gjedde A, Møller-Christensen V, Trolle D (1979) (eds.) Københavns Universitet 1479-1979. Bind VII. Det lægevidenskabelige Fakultet. Copenhagen: Københavns Universitet.
Gjedde A. (1983): Modulation of substrate transport to the brain. Disputats Københavns Universitet. Copenhagen: Medical Physiology Departement A, The Panum Institute
Hakim A, Gjedde A (1987) (eds.) Brain87: Proceedings of the Thirteenth International Symposium on Cerebral Blood Flow and Metabolism. New York: Lippincott-Raven.
Johannsen P, Gjedde A (2000) PET-skanning og demensudredning. Copenhagen: Pfizer A/S. ID number: OCLC463899907 or DBF 200208.
Gjedde A, Hansen SB, Knudsen GM, Paulson OB (2000) (eds.) Physiological Imaging of the Brain with PET. San Diego: Academic Press.ID Number: ISBN0122857518.
Ellemann K, Gjedde A., Hall N.M, Holm K., Madsen P.L., Møller M., Pedersen P.M., Rogvi-Hansen B. á, Sørensen P. (2003): Hjernen og bevidsthed, en oversigt over aktuel viden. Copenhagen: Hjerneforum. ID number: ISBN8798887017
Gjedde A., Graugaard C., Kjær T.W., Kristensen E., Mosbæk-Guildal A., Møllgård K, Pakkenberg B., Rogvi-Hansen B. á, Stødkilde-Jørgensen H. (2005): Hjernen og seksualitet. Copenhagen: Hjerneforum. ISBN8798887033
Binzer M., Gjedde A., Hall N.M., Kyllingsbæk S., Lindhardt J., Pedersen P.M., Rogvi-Hansen B. á, Rosenberg R., (2006): Hjernen vil bedrages. Copenhagen: Hjerneforum. ID number: ISBN8798887041
^Rodell A.B. (2003)(ed.) På sporet af det indre liv. PET i Århus 1993-2003. Aarhus: Det Sundhedsvidenskabelige Fællestrykkeri Aarhus Universitet.ID Number: ISBN8798977318.
