The race started and finished in Huy, with the finish line on the top of the final ascent of the Mur de Huy - one of three ascents of the Mur on the route.[2][3] There were 7 categorised climbs:
An early breakaway was captured by the peloton prior to the first ascent of the Côte de Cherave. On the penultimate climb of the Mur de Huy with around 35 kilometres to go, an elite group of riders including Annemiek van Vleuten of Movistar, Kasia Niewiadoma of Canyon–SRAM and Ashleigh Moolman-Pasio of AG Insurance–Soudal–Quick-Step attacks, going clear of the pack. However, Marlen Reusser and Vollering of SD Worx ensured that the group did not gain more than around 15 seconds, allowing them to be caught soon afterwards.[1]
On the final ascent of the Côte de Cherave, Vollering pushed hard - bringing a group of eleven riders including van Vleuten, Moolman-Pasio, Realini, Elise Chabbey of Canyon–SRAM, Liane Lippert of Movistar, and Mavi Garcia of Liv Racing TeqFind with her. However, none of the riders wished to push prior to the final climb of the Mur de Huy - a 1.3 km climb at 9.6% - allowing a larger group of riders to reform.[1]
Niewiadoma led the group towards the Mur, with Vollering overtaking her at the foot of the climb. Vollering then motored up the steep climb ahead of her rivals, winning by 5 seconds ahead of Lippert. Realini took third place after overtaking García with around 75 metres remaining.[1]
It was Vollering's first win at La Flèche Wallonne Féminine, and her third win of the season following victories at Strade Bianche Donne and the Amstel Gold Race.[1] Vollering also took the leader’s jersey of the UCI Women's World Tour following her win.[1]