The 2021 Wartburg Knights football team represented Wartburg College as a member of the American Rivers Conference (ARC) during the 2021 NCAA Division III football season. Led by first-year head coach Chris Winter, the Knights opened the season and Winters tenure with a win.[1] They opened conference play with a win over Coe[2] but finished the season with an overall record of 7–3 and a mark of 6–2 in the ARC, placing second.[3] The team played home games at Walston-Hoover Stadium in Waverly, Iowa.[4]