The 2021–22 NCAA Division II men's ice hockey season began on October 17, 2021 and concluded on March 5 of the following year. This was the 40th season of second-tier college ice hockey.
Championship: March 5 † indicates conference regular season champion * indicates conference tournament champion Note: three separate games between Franklin Pierce, Post, Saint Michael's and Stonehill were cancelled as a result of COVID-19 protocols.