29 April – Prime Minister Nuno Gomes Nabiam, Interior Minister Botche Candé, Secretary of State for Public Order Mario Fambé, and Secretary of State for Regional Integration Monica Buaro da Costa tested positive for COVID-19.[5][6]
May
1 May – The Minister of Public Health Antonio Deuna tested positive for COVID-19.[7]
June
16 June – It was reported by Reuters that 9% of health care workers have been infected with COVID-19. According to Joana Cortez, a WHO expert in the country, the three main Bissau hospitals are currently facing rooms filled with COVID-19 patients and a breakdown in essential medical services.[8]
26 June – President Umaro Sissoco Embaló announced a one-month extension of the state of emergency, but lifted the curfew.[9]