The division consists of three separate leagues, each containing 16 teams. Leagues A and B consist of teams with a license from the Voetbalfederatie Vlaanderen (VFV, the Flemish/Dutch speaking wing of the Belgian FA), while league C contains teams with a license from the Association des Clubs Francophones de Football (ACFF, the French-speaking wing of the RBFA). The champions from each of the three leagues will promote to the 2020–21 Belgian First Amateur Division. The fixtures were announced in early July 2019.
Oudenaarde was also relegated from the 2018–19 Belgian First Amateur Division after losing the Second Amateur Division promotion play-offs, where the team failed to regain its place in the First Amateur Division.
Merelbeke was promoted after winning the 2018–19 Belgian Third Amateur Division A.
Tienen was promoted after winning the 2018–19 Belgian Third Amateur Division B.
Namur Fosses was promoted after winning the 2018–19 Belgian Third Amateur Division C.
Stockay-Warfusée was promoted after winning the 2018–19 Belgian Third Amateur Division D.
Despite winning the relegation play-offs, Eppegem was also relegated due to the promotion of ACFF team Visé, forcing an extra VFV team to be relegated.
^ abcdefghiAalst, Cappellen, Diegem, Geel, Hades, Hasselt, Hoogstraten, Spouwen-Mopertingen and Vosselaar had played one match less at the time the competition was stopped, therefore their points were scaled up by a factor 23/22.
^On 18 January 2020, Vosselaar announced it would not be applying for a license to play in the national amateur leagues during the 2020–21 season due to the excessive financial costs. As a result, the team will be relegated to Belgian Provincial Leagues (but won't suffer any starting penalty as they will finish the season).[3]
^On 22 January 2020, due to financial difficulties, Geel announced that during the 2019–20 transfer window all players and technical staff have been released without any transfer fee, to avoid bankrupting the club. Youth players will play the remaining matches and management will devise a plan for the coming seasons.[3] Eventually, Geel did not receive a license for both the Second and Third Amateur divisions and should normally be relegating to the Belgian Provincial Leagues as well. Geel is, however, appealing the decision to not being awarded a license. If the appeal is successful, they will remain in the Belgian Second Amateur Division.
^On 28 January 2020, Duffel announced it would not be competing for the remainder of the season. As per the rules of the Belgian FA, all the results of Duffel were annulled and Duffel will be ranked last and penalized with a further relegation, starting the 2020–21 season at the first level of the Belgian Provincial Leagues (sixth level overall) with a nine-point penalty.[4][3]
^ abcdCouvin-Mariembourg, La Louvière, Solières and Tilleur had played one match less at the time the competition was stopped, therefore their points were scaled up by a factor 24/23.
^ abStockay and Verlaine had played two matches less at the time the competition was stopped, therefore their points were scaled up by a factor 24/22.
^Tilleur did not apply for a license and was therefore relegated to the Belgian Provincial Leagues.