The 2010–11 Cypriot Fourth Division was the 26th season of the Cypriot fourth-level football league. Ormideia FC won their 1st title.
Format
Fourteen teams participated in the 2010–11 Cypriot Fourth Division. All teams played against each other twice, once at their home and once away. The team with the most points at the end of the season were crowned champions. The first three teams were promoted to the 2011–12 Cypriot Third Division and the last three teams were relegated to regional leagues.
Point system
Teams received three points for a win, one point for a draw and zero points for a loss.