Number 3 seed Iowa State defeated number 1 seed Oklahoma 68–65 to win their 2nd championship and receive the conference's automatic bid to the 2001 NCAA tournament.
Seeding
The Tournament consisted of a 12 team single-elimination tournament with the top 4 seeds receiving a bye.[3]
‡ – Big 12 Conference regular season champions, and tournament No. 1 seed. # – Received a single-bye in the conference tournament. Overall records include all games played in the Big 12 Conference tournament.[4]