2-Methoxy-4-nitroaniline

2-Methoxy-4-nitroaniline
Names
Other names
4-Nitro-o-anisidine, 4-Nitroanisidine
Identifiers
Properties
C7H8N2O3
Molar mass 168.152 g·mol−1
Appearance yellow solid
Density 1.42 g/cm3[1]
Melting point 140–142 °C (284–288 °F; 413–415 K)
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).

2-Methoxy-4-nitroaniline is an organic compound with the formula O2NC6H3(OCH3)NH2.[2] It is one of four isomers of methoxynitroaniline. The compound is a precursor to the commercial Pigment Yellow 74.

Safety

It induces expression of some versions of cytochrome P450.[3]

References

  1. ^ Mehdi, S. (1992). "Structure of 2-methoxy-4-nitroaniline". Acta Crystallographica Section C Crystal Structure Communications. 48 (4): 749–751. Bibcode:1992AcCrC..48..749M. doi:10.1107/S0108270191010739.
  2. ^ Bao, Yuxin; Wu, Jiaxin; Zhao, Xi; Zhao, Hongkun (2020). "2-Methoxy-4-nitroaniline Solubility in Several Monosolvents: Measurement, Correlation, and Solvent Effect Analysis". Journal of Chemical & Engineering Data. 65 (2): 757–765. doi:10.1021/acs.jced.9b00991.
  3. ^ Degawa, Masakuni; Nakayama, Masafumi; Konno, Yoshihiro; Masubuchi, Kazuhiro; Yamazoe, Yasushi (1998). "2-Methoxy-4-nitroaniline and its isomers induce cytochrome P4501A (CYP1A) enzymes with different selectivities in the rat liver". Biochimica et Biophysica Acta (BBA) - General Subjects. 1379 (3): 391–398. doi:10.1016/S0304-4165(97)00118-9. PMID 9545601.