Elemen regulasi Bicoid 3′-UTR

Bicoid 3′-UTR regulatory element
Bicoid 3′-UTR regulatory element
	Stem-loop structure of the bicoid 3′-UTR regulatory element
Identifikasi
Rfam	RF00551
Data lain
tipe RNA	Cis-reg
Domain(s)	Insecta
PDB structures	PDBe

Elemen pengatur bicoid 3′-UTR adalah elemen pengatur mRNA yang mengontrol ekspresi gen protein bicoid pada lalat buah Drosophila melanogaster.

Elemen RNA terstruktur terdiri dari empat domain (dilambangkan sebagai II, III, IV dan V) dalam 3′UTR mRNA. Hal ini penting untuk transportasi yang benar dan lokalisasi mRNA bicoid selama diferensiasi oosit dan embrio, yang telah dipelajari paling teliti dalam pengembangan larva Drosophila melanogaster (lalat buah).^[1]^[2]^[3]^[4]

Referensi

^ Macdonald PM, Struhl G (December 1988). "cis-acting sequences responsible for anterior localization of bicoid mRNA in Drosophila embryos". Nature. 336 (6199): 595–598. Bibcode:1988Natur.336..595M. doi:10.1038/336595a0. PMID 3143913.
^ MacDonald PM (September 1990). "bicoid mRNA localization signal: phylogenetic conservation of function and RNA secondary structure". Development. 110 (1): 161–171. doi:10.1242/dev.110.1.161. PMID 2081457.
^ Seeger MA, Kaufman TC (September 1990). "Molecular analysis of the bicoid gene from Drosophila pseudoobscura: identification of conserved domains within coding and noncoding regions of the bicoid mRNA". The EMBO Journal. 9 (9): 2977–2987. doi:10.1002/j.1460-2075.1990.tb07490.x. PMC 552015 . PMID 1975239.
^ Brunel C, Ehresmann C (February 2004). "Secondary structure of the 3′ UTR of bicoid mRNA". Biochimie. 86 (2): 91–104. doi:10.1016/j.biochi.2004.01.002. PMID 15016447.

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[pmid3143913-1] Macdonald PM, Struhl G (December 1988). "cis-acting sequences responsible for anterior localization of bicoid mRNA in Drosophila embryos". Nature. 336 (6199): 595–598. Bibcode:1988Natur.336..595M. doi:10.1038/336595a0. PMID 3143913.

[pmid2081457-2] MacDonald PM (September 1990). "bicoid mRNA localization signal: phylogenetic conservation of function and RNA secondary structure". Development. 110 (1): 161–171. doi:10.1242/dev.110.1.161. PMID 2081457.

[pmid1975239-3] Seeger MA, Kaufman TC (September 1990). "Molecular analysis of the bicoid gene from Drosophila pseudoobscura: identification of conserved domains within coding and noncoding regions of the bicoid mRNA". The EMBO Journal. 9 (9): 2977–2987. doi:10.1002/j.1460-2075.1990.tb07490.x. PMC 552015 . PMID 1975239.

[4] Brunel C, Ehresmann C (February 2004). "Secondary structure of the 3′ UTR of bicoid mRNA". Biochimie. 86 (2): 91–104. doi:10.1016/j.biochi.2004.01.002. PMID 15016447.

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Elemen regulasi Bicoid 3′-UTR

Referensi

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