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CCR5
CCR5, (bahasa Inggris: chemokine receptor 5, CCR5) adalah pencerap kemokina dengan ligan, antara lain berupa RANTES, MIP-1α dan MIP-1β. CCR5 juga merupakan nama dari gen yang mengkodekan dari reseptor CC45. CCR5 terletak pada kromosom 3 pada lengan pendek (p) pada posisi 21. CCR5 terutama ada pada sel T, makrofaga, sel dendritik dan mikroglia. CCR5 memainkan peran penting pada respon peradangan terhadap infeksi, walaupun peran CCR5 untuk fungsi imun masih tidak jelas. HIV menggunakan CCR5 atau protein lainnya, CXCR4, untuk memasuki sel targetnya.
Referensi
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