Introduction: Children are the main value of any society, which plays a huge role in its development andprosperity. Meanwhile, they are the most vulnerable sector that have to be protected from negative physicaland mental factors as well as diseases. A wide range of factors can affect the health of children, especially intheir first year of life. Deep knowledge on those triggers may help to reduce the risk of developing differentpathological conditions among them.Materials and Method: An integrated analysis and risk assessment of different pathologies in 767 outpatientchildren under 1 year were cunducted. A survey of the parents of those children was also conducted. Theobjectivity of the information obtained is guaranteed by the directed application of the method and techniquesused in public health and healthcare, namely, medical-statistical analysis, sociological, psychological andexpert analysis.Results: Many childrenhad a low risk of developing chronic diseases, including those with a hereditarypredisposition and had a IIB health group, these are children with background of conditions and risk factorsthat can cause the formation of a chronic pathology. The third group of healthy children was representedby children with chronic pathology in the stage of compensation, the number of such babies was small(5.9±0.85%), as well as healthy babies with I (6.0±0.86%) and II A (4.2±0.72%) by health groups.Furthermore, more than half of the children of the first year of life had a normal functional state of the body.However, in 43% of cases, the functional state was impaired, which is manifested by the presence of variouspathological conditions.Conclusion: Comprehensive integrated approach and using evidence-based medicine principles for studyingthe medical conditions in children under 1 year-old can be valuable and help us to obtain reliable data on thehealth conditions and affecting risk factors.