Luteolin 7-O-glucuronosyltransferase

luteolin 7-O-glucuronosyltransferase
Identifiers
EC no.	2.4.1.189
CAS no.	115490-49-8
Databases
IntEnz	IntEnz view
BRENDA	BRENDA entry
ExPASy	NiceZyme view
KEGG	KEGG entry
MetaCyc	metabolic pathway
PRIAM	profile
PDB structures	RCSB PDB PDBe PDBsum
Gene Ontology	AmiGO / QuickGO
Search PMC articles PubMed articles NCBI proteins

In enzymology, a luteolin 7-O-glucuronosyltransferase (EC 2.4.1.189) is an enzyme that catalyzes the chemical reaction

UDP-glucuronate + luteolin ${\displaystyle \rightleftharpoons }$ UDP + luteolin 7-O-beta-D-glucuronide

Thus, the two substrates of this enzyme are UDP-glucuronate and luteolin, whereas its two products are UDP and luteolin 7-O-beta-D-glucuronide.

This enzyme belongs to the family of glycosyltransferases, specifically the hexosyltransferases. The systematic name of this enzyme class is UDP-glucuronate:luteolin 7-O-glucuronosyltransferase. Other names in common use include uridine diphosphoglucuronate-luteolin 7-O-glucuronosyltransferase, and LGT.

References

• Schulz M, Weissenbock G (1988). "3 specific UDP-glucuronate-flavone-glucuronosyl-transferases from primary leaves of Secale cereale". Phytochemistry. 27 (5): 1261–1267. doi:10.1016/0031-9422(88)80175-4.