Enzyme
In enzymology , a beta-ureidopropionase (EC 3.5.1.6 ) is an enzyme that catalyzes the chemical reaction
N-carbamoyl-beta-alanine + H2 O
⇌ ⇌ -->
{\displaystyle \rightleftharpoons }
beta-alanine + CO2 + NH3
Thus, the two substrates of this enzyme are N-carbamoyl-beta-alanine and H2 O , whereas its 3 products are beta-alanine , CO2 , and NH3 .
This enzyme belongs to the family of hydrolases , those acting on carbon-nitrogen bonds other than peptide bonds, specifically in linear amides. The systematic name of this enzyme class is N-carbamoyl-beta-alanine amidohydrolase . This enzyme participates in 3 metabolic pathways : pyrimidine metabolism , beta-alanine metabolism , and pantothenate and coenzyme A biosynthesis.
Structural studies
As of late 2007, 6 structures have been solved for this class of enzymes, with PDB accession codes 1R3N , 1R43 , 2V8D , 2V8G , 2V8H , and 2V8V .
References
Activity Regulation Classification Kinetics Types